Estamos realizando la búsqueda. Por favor, espere...
1582
37
170
29108
4409
2600
347
389
Abstract: The aim of this study is to assess the presence of substantia nigra (SN) hypoechogenicity in a cohort of Friedreich?s ataxia (FRDA) patients and its possible association with restless syndrome (RLS). Fourteen genetically confirmed FRDA patients and 14 sex- and age-matched healthy controls underwent transcranial sonography examination to evaluate the area of echogenicity of the SN. Both groups were clinically assessed with the essential and additional diagnostic criteria for RLS established by the International RLS Study Group. Ataxia was evaluated using the Scale for the Assessment and Rating of Ataxia. We did not find significant differences between the mean sum area of SN echogenicity in FRDA patients and in controls. Only one patient in the FDRA group and two control subjects showed SN hypoechogenicity. Two out of the 14 FDRA patients and one of the controls fulfilled diagnostic criteria for RLS. The areas of SN echogenicity in the two FRDA patients with RLS were the lowest found in this group. We conclude that our data do not support the notion that SN hypoechogenicity is related to FRDA itself, although it might be associated with RLS.
Autoría: Sierra M., Infante J., Berciano J.,
Fuente: The Cerebellum, 2013, 12(4), 437-440
Editorial: Springer
Fecha de publicación: 01/08/2013
Nº de páginas: 4
Tipo de publicación: Artículo de Revista
DOI: 10.1007/s12311-012-0434-y
ISSN: 1473-4230,1473-4222
Url de la publicación: https://doi.org/10.1007/s12311-012-0434-y
Leer publicación
MARIA SIERRA PEÑA
JON INFANTE CEBERIO
JOSE ANGEL BERCIANO BLANCO
Volver