Supplementary Movie S1. FRAPexperiment in which the quick recovery of mEGFP-JMJD3 puncta after photobleaching is observed. Supplementary Movie S2. FRAP experiment in which the aggregation of mEGFP-JMJD3 is appreciated by means of a reduced mobility after photobleaching. Supplementary Data file 1. Table depicting the parameters that assess the quality of the Chst8 4C-seq experiments for each sample as previously described. Briefly, the % of reads containing VP sequence should be above 90, the % of fragments that map in cis above 50, and the % of reads that map in unique sites within 1Mb around VP above 60. Supplementary Data file 2 and 3. Tables containing the quality measurements for each sample of the Ldlrad4 4C-seq (2) and Aopep 4C-seq (3) experiments, according to the parameters previously described. Briefly, the % of reads containing VP sequence should be above 90, the % of fragments that map in cis above 50, and the % of reads that map in unique sites within 1Mb around VP above 60.

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