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Regulación Espacial de Señales Ras-ERK en Cáncer

Publications
9
Projects
9
Thesis
14
Patents and technologies
1

Group manager: PEDRO CRESPO BARAJA

INST. DE BIOMEDICINA Y BIOTECNOLOGÍA DE CANTABRIA

FACULTAD DE MEDICINA- AV. CARDENAL HERRERA ORIA S/N

942 200959

Research lines

FUNCIONES Y REGULACION DE LA MAP KINASA MXI2 - Head: PEDRO CRESPO BARAJA
FUNCIONES Y REGULACION DE LAS PROTEINAS RAS - Head: PEDRO CRESPO BARAJA
REGULACION DEL FACTOR DE INTERCAMBIO RAS-GRF - Head: PEDRO CRESPO BARAJA

Operating laboratories

LABORATORIO DE BIOQUIMICA

Services

ANALISIS DE ACTIVIDAD DE PROTEINAS G Y KINASAS
ANALISIS INTERACCIONALES PROTEINA - PROTEINA
BIOLOGIA MOLECULAR BASICA
CARACTERIZACION DE DOMINIOS DE MEMBRANAS
CULTIVOS CELULARES

Collaborating Entities

BIRLA CARBON SPAIN, S.L.U.
FUNDACION CIENTIFICA DE LA ASOCIACION ESPAÑOLA CONTRA EL CANCER
INSTITUTO DE SALUD CARLOS III
MANCOMUNIDAD DE MUNICIPIOS SOSTENIBLES DE CANTABRIA
MINISTERIO DE CIENCIA, INNOVACION Y UNIVERSIDADES
SODERCAN, S.A.

Members Publications Projects Supervised Theses Patents and technologies

1 results

PEDRO CRESPO BARAJA

Group manager

Personal CSIC: Profesor de Investigación

INST. DE BIOMEDICINA Y BIOTECNOLOGÍA DE CANTABRIA

1 results

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Year of publication

9 results

ERK2 stimulates MYC transcription by anchoring CDK9 to the MYC promoter in a kinase activity–independent manner

Article

Science Signaling, 2023, 16, eadg4193

Authorship: LORENA AGUDO IBAÑEZ, MARTA MORANTE EZQUERRA, LUCIA GARCIA GUTIERREZ, ANDREA QUINTANILLA CAVIA, JAVIER RODRIGUEZ MARTINEZ, ALBERTO MUÑOZ, JAVIER LEON SERRANO, PEDRO CRESPO BARAJA

2023

Inhibiting ERK dimerization ameliorates BRAF-driven anaplastic thyroid cancer

Article

Cellular and Molecular Life Sciences : CMLS, 2022, 79, 504

Authorship: MIGUEL A. ZABALLOS, ADRIÁN ACUÑA-RUIZ, MARTA MORANTE EZQUERRA, GARCILASO RIESCO-EIZAGUIRRE, PEDRO CRESPO BARAJA, PILAR SANTISTEBAN

03/09/2022

The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function

Article

Oncogene . 2022 Jun;41(24):3341-3354

Authorship: L FRANCISCO LORENZO-MARTÍN, MAURICIO MENACHO-MÁRQUEZ, NATALIA FERNÁNDEZ-PAREJO, SONIA RODRÍGUEZ-FDEZ, GLORIA PASCUAL, ANTONIO ABAD, PEDRO CRESPO BARAJA, MERCEDES DOSIL, SALVADOR A BENITAH, XOSÉ R BUSTELO

2022

Immune checkpoint inhibitors and RAS?ERK pathway-targeted drugs as combined therapy for the treatment of melanoma

Article

Biomolecules, 2022, 12(11), 1562

Authorship: MARTA MORANTE EZQUERRA, ATANASIO PANDIELLA, PEDRO CRESPO BARAJA, ANA HERRERO MIER

2022

Ras and Other GTPases in Cancer: From Basic to Applied Research

Article

Front. Mol. Biosci. 8:804818

Authorship: CHO KWANG-JIN, RUI LIANG JIN, PEDRO CRESPO BARAJA, VERONICA ARAN

29/11/2021

ARID2 deficiency promotes tumor progression and is associated with higher sensitivity to chemotherapy in lung cancer

Article

Oncogene 2021 Apr;40(16):2923-2935

Authorship: THAIDY MORENO RODRIGUEZ, BEATRIZ MONTERDE MARTINEZ, LAURA GONZALEZ SILVA, ISABEL BETANCOR-FERNÁNDEZ, CARLOS REVILLA GOMEZ, ANTONIO MANUEL AGRAZ DOBLAS, JAVIER FREIRE, PABLO ISIDRO, LAURA QUEVEDO PALACIO, ROSA FERNANDA BLANCO FERNÁNDEZ, SANTIAGO MONTES-MORENO, LAURA CERECEDA, AURORA ASTUDILLO, BERTA CASAR MARTINEZ, PEDRO CRESPO BARAJA, CRISTINA MORALES TORRES, PAOLA SCAFFIDI, JAVIER GÓMEZ-ROMÁN, EDUARDO SALIDO, IGNACIO VARELA EGOCHEAGA

2021

Small molecule inhibition of ERK dimerization prevents tumorigenesis by RAS-ERK pathway oncogenes

Article

Cancer Cell, 2015, 28(2), 170-182

Authorship: ANA HERRERO MIER, ADAN PINTO FERNANDEZ, PAULA COLON BOLEA, BERTA CASAR MARTINEZ, MARY JONES, LORENA AGUDO IBAÑEZ, REBECA VIDAL CASADO, STEPHAN P. TENBAUM, PAOLO NUCIFORO, ELSA MARIA VALDIZAN RUIZ, ZOLTAN HORVATH, LASZLO ORFI, ANTONIO PINEDA LUCENA, EMILIE BONY, GYORGY KERI, GERMÁN RIVAS, ANGEL PAZOS CARRO, RAFAEL GOZALBES, HÉCTOR G. PALMER, ADAM HURLSTONE, PEDRO CRESPO BARAJA

10/08/2015