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Plasticidad Tisular Patológica

Publications
44
Projects
15
Thesis
12

Group manager: MARIA AMOR HURLE GONZALEZ

DEPARTAMENTO DE FISIOLOGÍA Y FARMACOLOGÍA

FACULTAD DE MEDICINA- AV. CARDENAL HERRERA ORIA S/N SANTANDER

942 201961

Research lines

DEPENDENCIA , TOLERANCIA Y SUPERSENSIBILIDAD A OPIACEOS : MECANISMOS MOLECULARES IMPLICADOS Y CONSECUENCIAS CONDUCTUALES - Head: MARIA AMOR HURLE GONZALEZ

Equipment

CRIOSTATO
ESTEREOMICROSCOPIO
MICROSCOPIO CON FOCAL
MICROSCOPIO DE FLUORESCENCIA
UNIDAD DE CULTIVOS CELULARES

Operating laboratories

LABORATORIO DE NEUROFARMACOLOGIA
ESTUDIOS FARMACOLOGICOS , NEUROQUIMICOS Y CONDUCTUALES EN ROEDORES

Collaborating Entities

AGENCIA ESTATAL DE INVESTIGACION
CONSEJERÍA DE EDUCACIÓN, FORMACIÓN PROFESIONAL Y UNIVERSIDADES
FUNDACION ESPAÑOLA DEL DOLOR
FUNDACION INSTITUTO DE INVESTIGACION MARQUES DE VALDECILLA
INSTITUTO DE SALUD CARLOS III
LA FUNDACIO LA MARATO DE TV3
MINISTERIO DE CIENCIA, INNOVACION Y UNIVERSIDADES

Members Publications Projects Supervised Theses

2 results

MARIA AMOR HURLE GONZALEZ

Group manager

Catedrático de Universidad

DEPARTAMENTO DE FISIOLOGÍA Y FARMACOLOGÍA

Publications
39
Projects
15
Thesis
14

JUAN FRANCISCO NISTAL HERRERA

Catedrático de Universidad

DEPARTAMENTO DE CIENCIAS MÉDICAS Y QUIRÚRGICAS

Publications
28
Projects
11
Thesis
7

2 results

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Year of publication

44 results

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Versican accumulation drives Nos2 induction and aortic disease in Marfan syndrome via Akt activation

Article

EMBO Molecular Medicine, 2024, 16, 132-157

Authorship: MARÍA JESÚS RUIZ-RODRÍGUEZ, JORGE OLLER, SARA MARTÍNEZ-MARTÍNEZ, IVÁN ALARCÓN-RUIZ, MARTA TORAL, YILIN SUN, ÁNGEL COLMENAR, MARÍA JOSÉ MÉNDEZ-OLIVARES, DOLORES LÓPEZ-MADERUELO, CHRISTINE B. KERN, JUAN FRANCISCO NISTAL HERRERA, ARTURO EVANGELISTA, GISELA TEIXIDO-TURA, MIGUEL R. CAMPANERO, JUAN MIGUEL REDONDO

2024

The stressed gut: region-specific immune and neuroplasticity changes in response to chronic psychosocial stress

Article

Journal of Neurogastroenterology and Motility, 2023, 29, 1

Authorship: BEATRIZ LOBO, MONICA TRAMULLAS FERNANDEZ, BEATE-C FINGER, KEVIN W. LOMASNEY, CAROLL BELTRAN, GERARD CLARKE, JAVIER SANTOS, NIALL P. HYLAND, TIMOTHY G. DINAN, JOHN F. CRYAN

2023

BMP7-based peptide agonists of BMPR1A protect the left ventricle against pathological remodeling induced by pressure overload

Article

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie, 2022, 149, 112910

Authorship: ANA BELEN SALIDO MEDINA, ARITZ GIL ONGAY, VICTOR EXPOSITO GARCIA, FERNANDO MARTÍNEZ, JUAN M. REDONDO, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA, RAQUEL GARCIA LOPEZ

01/05/2022

Spanish Registry of Acute Aortic Syndrome (RESA). Changes in therapeutic management and lower mortality in acute aortic syndrome

Article

Rev Esp Cardiol (Engl Ed) . 2022 Oct;75(10):816-824

Authorship: ARTUR EVANGELISTA MASIP, ÁNGELA LÓPEZ-SAINZ, ANTONIO JOSÉ BARROS MEMBRILLA, FRANCISCO CALVO IGLESIAS, JORDI LÓPEZ AYERBE, MANEL AZQUETA MOLLUNA, VÍCTOR X MOSQUERA RODRÍGUEZ, FRANCISCO ARREGUI MONTOYA, RUBÉN TARRÍO FERNÁNDEZ, ANA REVILLA ORODEA, VIOLETA SÁNCHEZ SÁNCHEZ, EVA MARÍA CANTERO PÉREZ, CARLOS FERRERA, DAVID TORAL SEPÚLVEDA, JUAN FRANCISCO NISTAL HERRERA, COVADONGA FERNÁNDEZ GOLFÍN, AUGUSTO SAO, JOSÉ RODRÍGUEZ-PALOMARES

2022

Identification of epigenetic interactions between microRNA-30c-5p and DNA methyltransferases in neuropathic pain

Article

International Journal of Molecular Sciences, 2022, 23(22), 13994

Authorship: RAQUEL FRANCES ROMERO, JORGE MATA GARRIDO, ROBERTO DE LA FUENTE ROYANO, MARIA CARCELEN LABRADOR, MIGUEL ANGEL LAFARGA COSCOJUELA, MARIA TERESA BERCIANO BLANCO, RAQUEL GARCIA LOPEZ, MARIA AMOR HURLE GONZALEZ, MONICA TRAMULLAS FERNANDEZ

2022

Estrous cycle and ovariectomy-induced changes in visceral pain are microbiota-dependent

Article

iScience . 2021 Jul 10;24(8):102850

Authorship: MONICA TRAMULLAS FERNANDEZ, JAMES M. COLLINS, PATRICK FITZGERALD, TIMOTHY G. DINAN, SIOBHAIN M. O`MAHONY, JOHN F. CRYAN

2021

Spanish experience with heart transplants from controlled donation after the circulatory determination of death using thoraco-abdominal normothermic regional perfusion and cold storage

Article

American journal of transplantation, 2021, 21, 1597-1602

Authorship: EDUARDO MIÑAMBRES GARCIA, MARIO ROYO-VILLANOVA, MARINA PÉREZ-REDONDO, ELISABETH COL, SUSANA VILLAR-GARCÍA, SERGIO J. CANOVAS, JUAN FRANCISCO NISTAL HERRERA, IRIS P. GARRIDO, MANUEL GÓMEZ-BUENO, MANUEL COBO BELAUSTEGUI, BEATRIZ DOMINGUEZ-GIL

14/12/2020

Sex-specific regulation of miR-29b in the myocardium under pressure overload is associated with differential molecular, structural and functional remodeling patterns in mice and patients with aortic stenosis

Article

Cells, 2020, 9(4), 833

Authorship: RAQUEL SILVIA GARCIA CEBALLOS, ANA B. SALIDO MEDINA, ARITZ GIL, DAVID MERINO, JENNY GÓMEZ, ANA VICTORIA VILLAR RAMOS, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA, FRANCISCO JESUS GONZALEZ VILCHEZ

30/03/2020

Evaluación no presencial en tiempos de COVID-19: análisis de resultados en el Grado en Medicina

Conference object

Edunovatic 2020. Conference Proceedings: 5th Virtual International Conference on Education, Innovation and ICT, December 10 - 11, 2020

Authorship: RAQUEL GARCIA LOPEZ, FRANCISCO JAVIER AYESTA AYESTA, MARIA AMOR HURLE GONZALEZ

2020

BMP-7 protects male and female rodents against neuropathic pain induced by nerve injury through a mechanism mediated by endogenous opioids

Article

Pharmacological Research 2019, 150, 104470

Authorship: ROSMARÍ DE LA PUERTA, MARIA CARCELEN LABRADOR, RAQUEL FRANCES ROMERO, ROBERTO DE LA FUENTE ROYANO, MARIA AMOR HURLE GONZALEZ, MONICA TRAMULLAS FERNANDEZ

01/12/2019

Experimental modelling of cardiac pressure overload hypertrophy: modified technique for precise, reproducible, safe and easy aortic arch banding-debanding in mice

Article

Scientific Reports, 2018 , 8 (1), 3167

Authorship: DAVID MERINO FERNANDEZ, ARITZ GIL, JENNY GÓMEZ, LUIS RUIZ, MIGUEL LLANO, RAQUEL GARCIA LOPEZ, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA

2018

MicroRNA-30c-5p modulates neuropathic pain in rodents

Article

Science Translational Medicine, 2018, 10(453), 6299

Authorship: MONICA TRAMULLAS FERNANDEZ, RAQUEL FRANCES ROMERO, ROBERTO DE LA FUENTE ROYANO, SARA VELATEGUI, MARIA CARCELEN LABRADOR, RAQUEL GARCIA LOPEZ, FRANCISCO JAVIER LLORCA DIAZ, MARIA AMOR HURLE GONZALEZ

01/08/2018

Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome

Article

Nature Medicine, 2017, 23(2), 200-212

Authorship: JORGE OLLER, NEREA MÉNDEZ-BARBERO, E JOSUE RUIZ, SILVIA VILLAHOZ, MARJOLIJN RENARD, LIZET I CANELAS, ANA M BRIONES, RUT ALBERCA, NOELIA LOZANO-VIDAL, MARIA AMOR HURLE GONZALEZ, DIANNA MILEWICZ, ARTURO EVANGELISTA, MERCEDES SALAICES, JUAN FRANCISCO NISTAL HERRERA, LUIS JESÚS JIMÉNEZ-BORREGUERO, JULIE DE BACKER, MIGUEL R CAMPANERO, JUAN MIGUEL REDONDO

2017

Potential value of microrna-30c as biomarker and therapeutic target for neuropathic pain

Conference object

Basic & Clinical Pharmacology & Toxicology, 2017, 121(S2), 28

Authorship: MONICA TRAMULLAS FERNANDEZ, RAQUEL FRANCES ROMERO, R. DE LA FUENTE, S. VELATEGUI, MARIA AMOR HURLE GONZALEZ

2017

Epigenetic mechanisms underlying neuropathic pain in rats

Conference object

Basic & Clinical Pharmacology & Toxicology, 2017, 121(S2), 85

Authorship: RAQUEL FRANCES ROMERO, JORGE MATA GARRIDO, MIGUEL ANGEL LAFARGA COSCOJUELA, MARIA TERESA BERCIANO BLANCO, MONICA TRAMULLAS FERNANDEZ, MARIA AMOR HURLE GONZALEZ

2017

BMP-7 attenuates left ventricular remodelling under pressure overload and facilitates reverse remodelling and functional recovery

Article

Cardiovascular Research, 2016, 110(3), 331-345

Authorship: DAVID MERINO FERNANDEZ, ANA VICTORIA VILLAR RAMOS, RAQUEL GARCIA LOPEZ, MONICA TRAMULLAS FERNANDEZ, LUIS RUIZ, CATALINA RIBAS, SOFÍA CABEZUDO, JUAN FRANCISCO NISTAL HERRERA, MARIA AMOR HURLE GONZALEZ

01/04/2016

Extracellular heat shock protein 90 binding to TGFbeta receptor I participates in TGFbeta-mediated collagen production in myocardial fibroblasts

Article

Cellular Signalling, 2016, 28(10), 1563-1579

Authorship: RAQUEL GARCIA LOPEZ, DAVID MERINO FERNANDEZ, JENNY M GÓMEZ, JUAN FRANCISCO NISTAL HERRERA, MARIA AMOR HURLE GONZALEZ, AITZIBER L. CORTAJARENA, ANA VICTORIA VILLAR RAMOS

2016

Desequilibrio de señalización BMP7 frente a TGF? en el remodelado del ventrículo izquierdo por sobrecarga de presión. Estudio traslacional

Conference object

Rev Esp Cardiol. 2015;68 Supl 1:386

Authorship: JUAN FRANCISCO NISTAL HERRERA, DAVID MERINO GARCÍA, ANA VICTORIA VILLAR RAMOS, RAQUEL GARCIA LOPEZ, MONICA TRAMULLAS FERNANDEZ, LUIS RUIZ GUERRERO, CATALINA RIBAS NÚÑEZ, MARIA AMOR HURLE GONZALEZ

2015

Influencia de la proteína de choque térmico 90 en la expresión de mediadores y dianas profibróticas del factor de crecimiento transformante beta en el corazón sometido a sobrecarga de presión

Conference object

Rev Esp Cardiol. 2015;68 Supl 1:1097

Authorship: RAQUEL GARCIA LOPEZ, JENNY GÓMEZ, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA, ANA VICTORIA VILLAR RAMOS

2015

The normal balance between antifibrotic Bmp7 and profibrotic Tgfâ signaling is lost on the pressure overloadinduced LV remodeling and can be modified favorably. A translational study

Conference object

Circulation, 2015, 132, A14298

Authorship: JUAN FRANCISCO NISTAL HERRERA, DAVID MERINO FERNANDEZ, ANA VICTORIA VILLAR RAMOS, RAQUEL GARCIA LOPEZ, MONICA TRAMULLAS FERNANDEZ, LUIS RUIZ GUERRERO, CATALINA RIBAS, MARIA AMOR HURLE GONZALEZ

2015

Bmp7 deficiency causes hyperalgesic phenotype and reduced response to morphine in a model of neuropathic pain

Conference object

Basic & Clinical Pharmacology & Toxicology, 2015, 117,(S2), 11

Authorship: MONICA TRAMULLAS FERNANDEZ, R. DE LA PUERTA, R. DE LA FUENTE, RAQUEL FRANCES ROMERO, AQUILINO LANTERO GARCIA, MARIA AMOR HURLE GONZALEZ

2015

p-SMAD2/3 and DICER promote pre-miR-21 processing during pressure overload-associated myocardial remodeling

Article

Biochimica et Biophysica Acta. Molecular Basis of Disease, 2015, 1852(7), 1520-30

Authorship: RAQUEL GARCIA LOPEZ, JUAN FRANCISCO NISTAL HERRERA, DAVID MERINO FERNANDEZ, NATHAN L PRICE, CARLOS FERNANDEZ HERNANDO, JAVIER BEAUMONT, ARANTXA GONZÁLEZ, MARIA AMOR HURLE GONZALEZ, ANA VICTORIA VILLAR RAMOS

2015

TGF-ß and opioid receptor signaling crosstalk results in improvement of endogenous and exogenous opioid analgesia under pathological pain conditions

Article

Journal of Neuroscience, 2014, 34(15), 5385-95

Authorship: AQUILINO LANTERO GARCIA, MONICA TRAMULLAS FERNANDEZ, MARIA FUENCISLA PILAR CUELLAR, ELSA MARIA VALDIZAN RUIZ, MARIA ROSA SANTILLAN FERNANDEZ, BERNARD P ROQUES, MARIA AMOR HURLE GONZALEZ

2014

Utilización de la simulación clínica en un Máster Interuniversitario en Estudio y Tratamiento del Dolor

Article

Revista de la Sociedad Española del Dolor, 2014, 21(3), 131-137

Authorship: ELENA ROSCALES SAN BARTOLOME, JOSE MARIA MAESTRE ALONSO, MARIA ROSA SANTILLAN FERNANDEZ, MARIA AMOR HURLE GONZALEZ, IGNACIO DEL MORAL VICENTE-MAZARIEGOS

2014

44 results

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