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Possible effects of some antipsychotic drugs on C-reactive protein in a drug-naïve psychotic sample

Abstract: Antipsychotic effects on C-reactive protein (CRP) have received little attention. This randomized open-label study investigated the possible effects of antipsychotics on CRP levels after 3 and 12 months of treatment in a Spanish drug-naïve sample taking haloperidol (N = 36 after 3 months), olanzapine (N = 36 after 3 months) or risperidone (N = 39 after 3 months). After 3 months and adjusting for differences in baseline CRP levels, baseline smoking and high baseline triglyceride levels, patients on haloperidol treatment had CRP levels that were 92.7% higher than those of patients on risperidone treatment (p = 0.009). After 12 months, only smoking was associated with increased CRP levels. Future studies need to verify that different antipsychotics may have differential effects on CRP levels, particularly after 3 months of treatment.

Otras publicaciones de la misma revista o congreso con autores/as de la Universidad de Cantabria

 Fuente: Schizophrenia Research, 2010, 121(1-3), 207-212

Editorial: Elsevier

 Fecha de publicación: 01/08/2010

Nº de páginas: 6

Tipo de publicación: Artículo de Revista

 DOI: 10.1016/j.schres.2010.06.002

ISSN: 0920-9964,1573-2509

Url de la publicación: https://doi.org/10.1016/j.schres.2010.06.002

Autores/as

DÍAZ, FRANCISCO J.

ROCIO PEREZ IGLESIAS

IGNACIO MATA PASTOR

OBDULIA MARTINEZ GARCIA

JOSE LUIS VAZQUEZ BARQUERO

LEÓN, JOSÉ DE

BENEDICTO CRESPO FACORRO