Brain matrix metalloproteinase-9 activity is altered in the corticosterone mouse model of depression

Article

Progress in neuro-psychopharmacology and biological psychiatry 120 (2023) 110624

 Authorship: SILVIA BREVIARIO, JULIA SENSERRICH GUERRERO, EVA ARIADNA FLORENSA ZANUY, EMILIO GARRO MARTINEZ, ALVARO MARCELINO DIAZ MARTINEZ, MARIA ELENA CASTRO FERNANDEZ, ANGEL PAZOS CARRO, MARIA FUENCISLA PILAR CUELLAR

 2023

5-ht4 receptors are not involved in the effects of fluoxetine in the corticosterone model of depression

Article

ACS Chemical Neuroscience, 2021 12(11), 2036-2044

 Authorship: JOSEP AMIGO RIU, EMILIO GARRO MARTINEZ, REBECA VIDAL CASADO, VALERIE COMPAN, MARIA FUENCISLA PILAR CUELLAR, ANGEL PAZOS CARRO, ALVARO MARCELINO DIAZ MARTINEZ, MARIA ELENA CASTRO FERNANDEZ

 2021

mTOR knockdown in the infralimbic cortex evokes a depressive-like state in mouse

Article

Int J Mol Sci . 2021 Aug 12;22(16):8671

 Authorship: EMILIO GARRO MARTINEZ, MARIA NEUS FULLANA, EVA ARIADNA FLORENSA ZANUY, JULIA SENSERRICH GUERRERO, VERÓNICA PAZ, ESTHER RUIZ-BRONCHAL, ALBERT ADELL CALDUCH, MARIA ELENA CASTRO FERNANDEZ, ALVARO MARCELINO DIAZ MARTINEZ, ANGEL PAZOS CARRO, ANALÍA BORTOLOZZI, MARIA FUENCISLA PILAR CUELLAR

 2021

Structural connectivity and subcellular changes after antidepressant doses of ketamine and Ro 25-6981 in the rat: an MRI and immuno-labeling study

Article

Brain Structure & Function, 2021, 226(8), 2603-2616

 Authorship: RAQUEL PASCUAL ANTÓN, ARANTXA BLASCO SERRA, EMMA MUÑOZ MORENO, MARIA FUENCISLA PILAR CUELLAR, EMILIO GARRO MARTINEZ, EVA ARIADNA FLORENSA ZANUY, XAVIER LÓPEZ GIL, VÍCTOR MANUEL CAMPA FERNÁNDEZ, GUADALUPE SORIA, ALBERT ADELL CALDUCH

 2021

Cannabidiol antidepressant-like effect in the lipopolysaccharide model in mice: Modulation of inflammatory pathways

Article

Biochemical Pharmacology, 2021, 185, 114433

 Authorship: EVA ARIADNA FLORENSA ZANUY, EMILIO GARRO MARTINEZ, ALBERT ADELL CALDUCH, MARIA ELENA CASTRO FERNANDEZ, ALVARO MARCELINO DIAZ MARTINEZ, ANGEL PAZOS CARRO, KARINA S. MAC-DOWELL, DAVID MARTÍN-HERNÁNDEZ, MARIA FUENCISLA PILAR CUELLAR

 01/03/2021

Opioid receptors mRNAs expression and opioids agonist-dependent G-protein activation in the rat brain following neuropathy

Article

Progress in Neuropsychopharmacology & Biological Psychiatry 99 (2020) 109857

 Authorship: MERITXELL LLORCA TORRALBA, MARIA FUENCISLA PILAR CUELLAR, GISELA DA SILVA BORGES, JUAN A. MICO, ESTHER BERROCOSO

 20/04/2020

Increased vulnerability to impulsive behavior after streptococcal antigen exposure and antibiotic treatment in rats

Article

Brain, Behavior and Immunity, 2020, 89, 675-688

 Authorship: SANTIAGO MORA, ELENA MARTÍN GONZÁLEZ, ÁNGELES PRADOS PARDO, JOAQUÍN MORENO, MARÍA JOSÉ LÓPEZ, MARIA FUENCISLA PILAR CUELLAR, MARIA ELENA CASTRO FERNANDEZ, ALVARO MARCELINO DIAZ MARTINEZ, PILAR FLORES, MARGARITA MORENO

 01/10/2020

ß-Catenin Role in the Vulnerability/Resilience to Stress-Related Disorders Is Associated to Changes in the Serotonergic System

Article

Mol Neurobiol , 57 (3), 1704-1715 Mar 2020

 Authorship: EMILIO GARRO MARTINEZ, REBECA VIDAL CASADO, ALBERT ADELL CALDUCH, ALVARO MARCELINO DIAZ MARTINEZ, MARIA ELENA CASTRO FERNANDEZ, JOSEP AMIGO RIU, RAQUEL GUTIÉRREZ LANZA, EVA ARIADNA FLORENSA ZANUY, LAURA GÓMEZ-ACERO, M. MARK TAKETO, ANGEL PAZOS CARRO, MARIA FUENCISLA PILAR CUELLAR

 2020

Targeting B-Catenin in GLAST-Expressing Cells: Impact on Anxiety and Depression-Related Behavior and Hippocampal Proliferation

Article

Mol Neurobiol. 2019 Jan;56(1):553-566

 Authorship: REBECA VIDAL CASADO, EMILIO GARRO MARTINEZ, ALVARO MARCELINO DIAZ MARTINEZ, MARIA ELENA CASTRO FERNANDEZ, EVA ARIADNA FLORENSA ZANUY, M. MARK TAKETO, ANGEL PAZOS CARRO, MARIA FUENCISLA PILAR CUELLAR

 01/01/2019

Opioid Activity in the Locus Coeruleus Is Modulated by Chronic Neuropathic Pain

Article

Mol Neurobiol. 2019 Jun;56(6):4135-4150

 Authorship: MERITXELL LLORCA TORRALBA, MARIA FUENCISLA PILAR CUELLAR, LIDIA BRAVO, CRISTINA BRUZOS CIDON, MARÍA TORRECILLA, JUAN A. MICO, LUISA UGEDO, EMILIO GARRO MARTINEZ, ESTHER BERROCOSO

 2019

S 47445 counteracts the behavioral manifestations and hippocampal neuroplasticity changes in bulbectomized mice

Article

Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jul 13;93:205-213

 Authorship: MARIA FUENCISLA PILAR CUELLAR, MARIA ELENA CASTRO FERNANDEZ, SYLVIE BRETIN, ELISABETH MOCAER, ANGEL PAZOS CARRO, ALVARO MARCELINO DIAZ MARTINEZ

 01/07/2019

Effect of cannabis on weight and metabolism in first-episode non-affective psychosis: results from a three-year longitudinal study

Article

Journal of Psychopharmacology, 2019, 33(3), 284-294

 Authorship: JAVIER VAZQUEZ BOURGON, MARIA ESTHER SETIEN SUERO, MARIA FUENCISLA PILAR CUELLAR, RODRIGO ROMERO JIMENEZ, VICTOR ORTIZ GARCIA DE LA FOZ, MARIA ELENA CASTRO FERNANDEZ, BENEDICTO CRESPO FACORRO

 2019

Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics

Article

Translational Psychiatry, 2019, 9(1), 306

 Authorship: FULGENCIO RUSO-JULVE, ANA POMBERO, MARIA FUENCISLA PILAR CUELLAR, NURIA GARCÍA-DÍAZ, RAQUEL GARCIA-LOPEZ, MARÍA JUNCAL-RUIZ, MARIA ELENA CASTRO FERNANDEZ, ALVARO MARCELINO DIAZ MARTINEZ, JAVIER VAZQUEZ BOURGON, AGUSTÍN GARCÍA-BLANCO, EMILIO GARRO-MARTINEZ, HELENA PISONERO, ALICIA ESTIRADO, ROSA AYESA-ARRIOLA, JUAN LÓPEZ-GIMÉNEZ, FEDERICO MAYOR JR., ELSA VALDIZÁN, JAVIER MEANA, JAVIER GONZALEZ-MAESO, SALVADOR MARTÍNEZ, JOSE PEDRO VAQUE DIEZ, BENEDICTO CRESPO FACORRO

 2019

The endocannabinoid system in mental disorders: Evidence from human brain studies

Article

Biochemical Pharmacology, 2018, 157, 97-107

 Authorship: INÉS IBARRA LECUE, MARIA FUENCISLA PILAR CUELLAR, CAROLINA MUGURUZA, EVA ARIADNA FLORENSA ZANUY, ALVARO MARCELINO DIAZ MARTINEZ, LEYRE URIGÜEN, MARIA ELENA CASTRO FERNANDEZ, ANGEL PAZOS CARRO, LUIS F. CALLADO

 01/11/2018

Selective up-regulation of cannabinoid CB1 receptor coupling to Go-proteins in suicide victims with mood disorders

Article

Biochemical Pharmacology, 2018, 157, 258-265

 Authorship: SUSANA MATO SANTOS, MARIA FUENCISLA PILAR CUELLAR, ELSA MARIA VALDIZAN RUIZ, JAVIER GONZÁLEZ MAESO, RAFAEL RODRÍGUEZ PUERTAS, JAVIER MEANA, JOAN SALLÉS, BENEDICTO CRESPO FACORRO, ANGEL PAZOS CARRO

 01/11/2018

Signaling pathways responsible for the rapid antidepressant-like effects of a GluN2A-preferring NMDA receptor antagonist

Article

Transl Psychiatry. 2018 Apr 18;8(1):84

 Authorship: MARTA GORDILLO SALAS, MARIA FUENCISLA PILAR CUELLAR, YVES P. AUBERSON, ALBERT ADELL

 01/04/2018

Enhanced stress response in 5-HT1AR overexpressing mice: altered HPA function and hippocampal long-term potentiation

Article

ACS Chemical Neuroscience, 2017, 8(11), 2393-2401

 Authorship: MARIA FUENCISLA PILAR CUELLAR, REBECA VIDAL, ALVARO MARCELINO DIAZ MARTINEZ, EMILIO GARRO MARTINEZ, RAQUEL LINGE MENDEZ, MARIA ELENA CASTRO FERNANDEZ, ROBERT HABERZETTL, HEIDRUN FINK, BETTINA BERT, JAN BROSDA, BEATRIZ ROMERO PRESNO, BENEDICTO CRESPO FACORRO, ANGEL PAZOS CARRO

 15/11/2017

Antidepressant-like effects of the AMPA potentiator S47445 are associated with changes in hippocampal BDNF and mTOR signaling in bulbectomy mouse model

Conference object

EUROPEAN NEUROPSYCHOPHARMACOLOGY 2017 Vol.27 (Supl.4):S775

 Authorship: MARIA FUENCISLA PILAR CUELLAR, MARIA ELENA CASTRO FERNANDEZ, S. BRETIN, E. MOCAER, ANGEL PAZOS CARRO, ALVARO MARCELINO DIAZ MARTINEZ

 2017

Effect of mTOR silencing in mouse infralimbic cortex on depressive-like behaviour

Conference object

EUROPEAN NEUROPSYCHOPHARMACOLOGY 2017 Vol.27 (Supl.4):S774-S775

 Authorship: EMILIO GARRO MARTINEZ, N. FULLANA, V. PAZ, E. RUIZ, A. BORTOLOZZI, ANGEL PAZOS CARRO, MARIA FUENCISLA PILAR CUELLAR

 2017

Therapeutic antidepressant potential of a conjugated siRNA silencing the serotonin transporter after intranasal administration

Article

Mol Psychiatry. 2016 Mar;21(3):328-38

 Authorship: A FERRES COY, M GALOFRÉ, MARIA FUENCISLA PILAR CUELLAR, V PAZ, E RUIZ BRONCHAL, L CAMPA, ANGEL PAZOS CARRO, JR CASO, JC LEZA, G ALVARADO, A MONTEFELTRO, ELSA MARIA VALDIZAN RUIZ, F ARTIGAS, A BORTOLOZZI

 2016

Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors

Article

Neuropharmacology. 2016 Apr;103:16-26

 Authorship: RAQUEL LINGE MENDEZ, LAURA JIMÉNEZ SÁNCHEZ, LETICIA CAMPA, MARIA FUENCISLA PILAR CUELLAR, REBECA VIDAL CASADO, ANGEL PAZOS CARRO, ALBERT ADELL CALDUCH, ALVARO MARCELINO DIAZ MARTINEZ

 2016

The absence of 5-HT4 receptors modulates depression- and anxiety-like responses and influences the response of fluoxetine in olfactory bulbectomised mice: Adaptive changes in hippocampal neuroplasticity markers and 5-HT1A autoreceptor

Article

Neuropharmacology. 2016 Dec;111:47-58

 Authorship: JOSEP AMIGO RIU, ALVARO MARCELINO DIAZ MARTINEZ, MARIA FUENCISLA PILAR CUELLAR, R VIDAL, A MARTÍN, V COMPAN, ANGEL PAZOS CARRO, MARIA ELENA CASTRO FERNANDEZ

 2016

Radioligand Binding Detection of Receptors in Brain Membranes

Book part

Receptor and Ion Channel Detection in the Brain: Methods and Protocols

 Authorship: MARIA FUENCISLA PILAR CUELLAR, ALVARO MARCELINO DIAZ MARTINEZ, EMILIO GARRO MARTINEZ, ALICIA MARTIN REBOLLO, BEATRIZ ROMERO PRESNO, ELSA MARIA VALDIZAN RUIZ

 2016

Principal component analysis applied to the identification of spectral variations in depressed mouse brain

Conference object

Proceedings Advanced Photonics 2015: 27 June–1 July 2015, Boston, Massachusetts, United States

 Authorship: EUSEBIO REAL PEÑA, MARIA FUENCISLA PILAR CUELLAR, REBECA VIDAL CASADO, ELSA MARIA VALDIZAN RUIZ, ANGEL PAZOS CARRO, DAVID HERNANDEZ MANRIQUE, JOSE MIGUEL LOPEZ HIGUERA, OLGA MARIA CONDE PORTILLA

 2015

CARACTERIZACION DE UN MODELO ANIMAL DE DEPRESION INTEGRANDO OBESIDAD E INFLAMACION: EFECTO DEL CANNABIDIOL Pry PID2021-127497OB-I00 financiado por MICIU/AEI /10.13039/501100011033 y por FEDER, UE

Typology: Competitive national public projects

Start year: 2022

METALOPROTEINASA-9 Y DEPRESION:ESTUDIO EN MODELO ANIMAL Y MUESTRAS CEREBRALES HUMANAS POSTMORTEM,Y PAPEL EN EL MECANISMO DE ACCION DE ANTIDEPRESIVOS DE ACCION RAPIDA.RTI2018-097534-B-I00/MCIN/AEI/10.13039/501100011033/ FEDER"Una manera de hacer Europa"

 Bases Neurobiológicas Del Mecanismo De Acción De Fármacos Sobre El Sistema Nervioso Central

 INST. DE BIOMEDICINA Y BIOTECNOLOGÍA DE CANTABRIA

Heads: ANGEL PAZOS CARRO, MARIA FUENCISLA PILAR CUELLAR

Typology: Competitive national public projects

Start year: 2019

CANNABIDIOL COMO ACELERADOR DE LA RESPUESTA FARMACOLOGICA ANTIDEPRESIVA: UNA VIA HACIA LA IDENTIFICACIÓN DE LOS MECANISMOS CELULARES IMPLICADOS EN LA DEPRESIÓN (SAF2015-67457-R) (MINECO/FEDER, UE)

 Bases Neurobiológicas Del Mecanismo De Acción De Fármacos Sobre El Sistema Nervioso Central

 INST. DE BIOMEDICINA Y BIOTECNOLOGÍA DE CANTABRIA

Head: ANGEL PAZOS CARRO

Typology: Competitive national public projects

Start year: 2016

MECANISMOS DE NEUROPLASTICIDAD INVOLUCRADOS EN LA RESPUESTA ANTIDEPRESIVA RÁPIDA DE LOS AGONISTAS DE RECEPTOR 5-HT4: PAPEL DE LAS VÍAS DE WNT-BETA-CATENINA Y MTOR (SAF2011-25020)

 Bases Neurobiológicas Del Mecanismo De Acción De Fármacos Sobre El Sistema Nervioso Central

 INST. DE BIOMEDICINA Y BIOTECNOLOGÍA DE CANTABRIA

Head: ANGEL PAZOS CARRO

Typology: Competitive national public projects

Start year: 2012

Metaloproteinasa-9 y depresión: estudio en un modelo animal y en muestras cerebrales humanas post-mortem, y papel en el mecanismo de acción de antidepresivos de acción rápida

 Authorship: JULIA SENSERRICH GUERRERO

 Supervision: MARIA ELENA CASTRO FERNANDEZ , MARIA FUENCISLA PILAR CUELLAR 

 Defense date: 17/03/2023

Cannabidiol como antidepresivo de acción rápida: identificación de los mecanismos moleculares implicados en su efecto antidepresivo

 Authorship: EVA ARIADNA FLORENSA ZANUY

 Supervision: ALVARO MARCELINO DIAZ MARTINEZ , MARIA FUENCISLA PILAR CUELLAR 

 Defense date: 13/04/2021

PAPEL DE LAS VÍAS DE SEÑALIZACIÓN DE mTOR Y B-CATENINA COMO DIANAS MOLECULARES PARA EL DESARROLLO DE ANTIDEPRESIVOS DE ACCIÓN RÁPIDA.

 Authorship: EMILIO GARRO MARTÍNEZ

 Supervision: ANGEL PAZOS CARRO , MARIA FUENCISLA PILAR CUELLAR 

 Defense date: 27/10/2017