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Detalle Investigador

MARIA ELENA CASTRO FERNANDEZ

Publications
41
Projects
7
Thesis
3

maria.castro@unican.es

Edificio IBBTEC. c/ Albert Einstein, 22 (PCTCAN). 39011 Santander

Profesor Titular de Universidad

Doctor en Farmacia

Bases Neurobiológicas Del Mecanismo De Acción De Fármacos Sobre El Sistema Nervioso Central

INST. DE BIOMEDICINA Y BIOTECNOLOGÍA DE CANTABRIA

Specialty areas: FARMACOLOGIA

Identifiers

View teaching activity

Other names in publications

Castro, E.
Castro, ME
Castro, Maria Elena
Castro, M. Elena
Castro, M. E.
Castro, Maria E.
Castro, Ma Elena

Publications Projects Supervised Theses

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41 results

1 of 2

Brain matrix metalloproteinase-9 activity is altered in the corticosterone mouse model of depression

Article

Progress in neuro-psychopharmacology and biological psychiatry 120 (2023) 110624

Authorship: SILVIA BREVIARIO, JULIA SENSERRICH GUERRERO, EVA ARIADNA FLORENSA ZANUY, EMILIO GARRO MARTINEZ, ALVARO MARCELINO DIAZ MARTINEZ, MARIA ELENA CASTRO FERNANDEZ, ANGEL PAZOS CARRO, MARIA FUENCISLA PILAR CUELLAR

2023

Inhibition of prolyl oligopeptidase restores prohibitin 2 levels in psychosis models: relationship to cognitive deficits in schizophrenia

Article

International Journal of Molecular Sciences, 2023, 2487), 6016

Authorship: ÈLIA VILA, RAQUEL PINACHO, ROGER PRADES, TERESA TARRAGÓ, MARIA ELENA CASTRO FERNANDEZ, EVA MUNARRIZ-CUEZVA, J. JAVIER MEANA, ANIA EUGUI-ANTA, MÒNICA ROLDAN, AMÉRICA VERA-MONTECINOS, BELÉN RAMOS

2023

5-ht4 receptors are not involved in the effects of fluoxetine in the corticosterone model of depression

Article

ACS Chemical Neuroscience, 2021 12(11), 2036-2044

Authorship: JOSEP AMIGO RIU, EMILIO GARRO MARTINEZ, REBECA VIDAL CASADO, VALERIE COMPAN, MARIA FUENCISLA PILAR CUELLAR, ANGEL PAZOS CARRO, ALVARO MARCELINO DIAZ MARTINEZ, MARIA ELENA CASTRO FERNANDEZ

2021

mTOR knockdown in the infralimbic cortex evokes a depressive-like state in mouse

Article

Int J Mol Sci . 2021 Aug 12;22(16):8671

Authorship: EMILIO GARRO MARTINEZ, MARIA NEUS FULLANA, EVA ARIADNA FLORENSA ZANUY, JULIA SENSERRICH GUERRERO, VERÓNICA PAZ, ESTHER RUIZ-BRONCHAL, ALBERT ADELL CALDUCH, MARIA ELENA CASTRO FERNANDEZ, ALVARO MARCELINO DIAZ MARTINEZ, ANGEL PAZOS CARRO, ANALÍA BORTOLOZZI, MARIA FUENCISLA PILAR CUELLAR

2021

Cannabidiol antidepressant-like effect in the lipopolysaccharide model in mice: Modulation of inflammatory pathways

Article

Biochemical Pharmacology, 2021, 185, 114433

Authorship: EVA ARIADNA FLORENSA ZANUY, EMILIO GARRO MARTINEZ, ALBERT ADELL CALDUCH, MARIA ELENA CASTRO FERNANDEZ, ALVARO MARCELINO DIAZ MARTINEZ, ANGEL PAZOS CARRO, KARINA S. MAC-DOWELL, DAVID MARTÍN-HERNÁNDEZ, MARIA FUENCISLA PILAR CUELLAR

01/03/2021

Increased vulnerability to impulsive behavior after streptococcal antigen exposure and antibiotic treatment in rats

Article

Brain, Behavior and Immunity, 2020, 89, 675-688

Authorship: SANTIAGO MORA, ELENA MARTÍN GONZÁLEZ, ÁNGELES PRADOS PARDO, JOAQUÍN MORENO, MARÍA JOSÉ LÓPEZ, MARIA FUENCISLA PILAR CUELLAR, MARIA ELENA CASTRO FERNANDEZ, ALVARO MARCELINO DIAZ MARTINEZ, PILAR FLORES, MARGARITA MORENO

01/10/2020

ß-Catenin Role in the Vulnerability/Resilience to Stress-Related Disorders Is Associated to Changes in the Serotonergic System

Article

Mol Neurobiol , 57 (3), 1704-1715 Mar 2020

Authorship: EMILIO GARRO MARTINEZ, REBECA VIDAL CASADO, ALBERT ADELL CALDUCH, ALVARO MARCELINO DIAZ MARTINEZ, MARIA ELENA CASTRO FERNANDEZ, JOSEP AMIGO RIU, RAQUEL GUTIÉRREZ LANZA, EVA ARIADNA FLORENSA ZANUY, LAURA GÓMEZ-ACERO, M. MARK TAKETO, ANGEL PAZOS CARRO, MARIA FUENCISLA PILAR CUELLAR

2020

Targeting B-Catenin in GLAST-Expressing Cells: Impact on Anxiety and Depression-Related Behavior and Hippocampal Proliferation

Article

Mol Neurobiol. 2019 Jan;56(1):553-566

Authorship: REBECA VIDAL CASADO, EMILIO GARRO MARTINEZ, ALVARO MARCELINO DIAZ MARTINEZ, MARIA ELENA CASTRO FERNANDEZ, EVA ARIADNA FLORENSA ZANUY, M. MARK TAKETO, ANGEL PAZOS CARRO, MARIA FUENCISLA PILAR CUELLAR

01/01/2019

S 47445 counteracts the behavioral manifestations and hippocampal neuroplasticity changes in bulbectomized mice

Article

Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jul 13;93:205-213

Authorship: MARIA FUENCISLA PILAR CUELLAR, MARIA ELENA CASTRO FERNANDEZ, SYLVIE BRETIN, ELISABETH MOCAER, ANGEL PAZOS CARRO, ALVARO MARCELINO DIAZ MARTINEZ

01/07/2019

Role of serotonin and noradrenaline in the rapid antidepressant action of ketamine

Article

ACS Chemical Neuroscience, 2019 10(7), 3318-3326

Authorship: XAVIER LÓPEZ-GIL, LAURA JIMÉNEZ-SÁNCHEZ, LETICIA CAMPA, MARIA ELENA CASTRO FERNANDEZ, CLARA FRAGO, ALBERT ADELL CALDUCH

2019

Effect of cannabis on weight and metabolism in first-episode non-affective psychosis: results from a three-year longitudinal study

Article

Journal of Psychopharmacology, 2019, 33(3), 284-294

Authorship: JAVIER VAZQUEZ BOURGON, MARIA ESTHER SETIEN SUERO, MARIA FUENCISLA PILAR CUELLAR, RODRIGO ROMERO JIMENEZ, VICTOR ORTIZ GARCIA DE LA FOZ, MARIA ELENA CASTRO FERNANDEZ, BENEDICTO CRESPO FACORRO

2019

Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics

Article

Translational Psychiatry, 2019, 9(1), 306

Authorship: FULGENCIO RUSO-JULVE, ANA POMBERO, MARIA FUENCISLA PILAR CUELLAR, NURIA GARCÍA-DÍAZ, RAQUEL GARCIA-LOPEZ, MARÍA JUNCAL-RUIZ, MARIA ELENA CASTRO FERNANDEZ, ALVARO MARCELINO DIAZ MARTINEZ, JAVIER VAZQUEZ BOURGON, AGUSTÍN GARCÍA-BLANCO, EMILIO GARRO-MARTINEZ, HELENA PISONERO, ALICIA ESTIRADO, ROSA AYESA-ARRIOLA, JUAN LÓPEZ-GIMÉNEZ, FEDERICO MAYOR JR., ELSA VALDIZÁN, JAVIER MEANA, JAVIER GONZALEZ-MAESO, SALVADOR MARTÍNEZ, JOSE PEDRO VAQUE DIEZ, BENEDICTO CRESPO FACORRO

2019

The endocannabinoid system in mental disorders: Evidence from human brain studies

Article

Biochemical Pharmacology, 2018, 157, 97-107

Authorship: INÉS IBARRA LECUE, MARIA FUENCISLA PILAR CUELLAR, CAROLINA MUGURUZA, EVA ARIADNA FLORENSA ZANUY, ALVARO MARCELINO DIAZ MARTINEZ, LEYRE URIGÜEN, MARIA ELENA CASTRO FERNANDEZ, ANGEL PAZOS CARRO, LUIS F. CALLADO

01/11/2018

Enhanced stress response in 5-HT1AR overexpressing mice: altered HPA function and hippocampal long-term potentiation

Article

ACS Chemical Neuroscience, 2017, 8(11), 2393-2401

Authorship: MARIA FUENCISLA PILAR CUELLAR, REBECA VIDAL, ALVARO MARCELINO DIAZ MARTINEZ, EMILIO GARRO MARTINEZ, RAQUEL LINGE MENDEZ, MARIA ELENA CASTRO FERNANDEZ, ROBERT HABERZETTL, HEIDRUN FINK, BETTINA BERT, JAN BROSDA, BEATRIZ ROMERO PRESNO, BENEDICTO CRESPO FACORRO, ANGEL PAZOS CARRO

15/11/2017

Chronic citalopram administration desensitizes prefrontal cortex but not somatodendritic ?2-adrenoceptors in rat brain

Article

Neuropharmacology. 2017 Mar 1;114:114-122

Authorship: BEGOÑA FERNÁNDEZ PASTOR, JORGE E. ORTEGA, LAURA GRANDOSO, MARIA ELENA CASTRO FERNANDEZ, LUISA UGEDO, ANGEL PAZOS CARRO, J. JAVIER MEANA

2017

Antidepressant-like effects of the AMPA potentiator S47445 are associated with changes in hippocampal BDNF and mTOR signaling in bulbectomy mouse model

Conference object

EUROPEAN NEUROPSYCHOPHARMACOLOGY 2017 Vol.27 (Supl.4):S775

Authorship: MARIA FUENCISLA PILAR CUELLAR, MARIA ELENA CASTRO FERNANDEZ, S. BRETIN, E. MOCAER, ANGEL PAZOS CARRO, ALVARO MARCELINO DIAZ MARTINEZ

2017

The glial phosphorylase of glycogen isoform is reduced in the dorsolateral prefrontal cortex in chronic schizophrenia

Article

Schizophr Res. 2016 Nov;177(1-3):37-43

Authorship: RAQUEL PINACHO, ELIA VILA, ROGER PRADES, TERESA TARRAGÓ, MARIA ELENA CASTRO FERNANDEZ, ISIDRE FERRER, BELÉN RAMOS

2016

The absence of 5-HT4 receptors modulates depression- and anxiety-like responses and influences the response of fluoxetine in olfactory bulbectomised mice: Adaptive changes in hippocampal neuroplasticity markers and 5-HT1A autoreceptor

Article

Neuropharmacology. 2016 Dec;111:47-58

Authorship: JOSEP AMIGO RIU, ALVARO MARCELINO DIAZ MARTINEZ, MARIA FUENCISLA PILAR CUELLAR, R VIDAL, A MARTÍN, V COMPAN, ANGEL PAZOS CARRO, MARIA ELENA CASTRO FERNANDEZ

2016

Autoradiographic Visualization of G Protein-Coupled Receptors in Brain

Book part

Receptor and Ion Channel Detection in the Brain: Methods and Protocols

Authorship: REBECA VIDAL CASADO, RAQUEL LINGE MENDEZ, MARIA JOSEFA CASTILLO DIAZ, JOSEP AMIGO RIU, ELSA MARIA VALDIZAN RUIZ, MARIA ELENA CASTRO FERNANDEZ

2016

Signaling pathways involved in antidepressant-induced cell proliferation and synaptic plasticity

Article

Current Pharmaceutical Design, 2014, 20(23), 3776-3794

Authorship: MARIA FUENCISLA PILAR CUELLAR, REBECA VIDAL CASADO, ALVARO MARCELINO DIAZ MARTINEZ, MARIA ELENA CASTRO FERNANDEZ, SEVERIANO DOS ANJOS VILABOA, VERONICA INES VARGAS, BEATRIZ ROMERO PRESNO, ELSA MARIA VALDIZAN RUIZ

2014

Serotonin 5-HT4 receptors: A new strategy for developing fast acting antidepressants?

Article

Curr Pharm Des. 2014;20(23):3751-62

Authorship: REBECA VIDAL CASADO, MARIA ELENA CASTRO FERNANDEZ, MARIA FUENCISLA PILAR CUELLAR, JESUS PASCUAL BRAZO, ALVARO MARCELINO DIAZ MARTINEZ, MARIA LUISA ROJO ANTUÑA, RAQUEL LINGE MENDEZ, ALICIA MARTÍN, ELSA MARIA VALDIZAN RUIZ, ANGEL PAZOS CARRO

2014

Serotonin 5-HT4 receptors: A new strategy for developing fast acting antidepressants?

Article

Current Pharmaceutical Design, 2014, 20(23):3751-3762

Authorship: ALVARO MARCELINO DIAZ MARTINEZ, ALICIA MARTIN REBOLLO, ELSA MARIA VALDIZAN RUIZ, ANGEL PAZOS CARRO, MARIA ELENA CASTRO FERNANDEZ, MARIA FUENCISLA PILAR CUELLAR

2014

Effects of chronic cannabidiol on serotonin/glutamate cortical release and molecular signaling pathways in bulbectomised depressed mice

Conference object

European Neuropsychopharmacology . Volume 24, Supplement 2, October 2014, Pages S450

Authorship: RAQUEL LINGE MENDEZ, L. JIMÉNEZ SÁNCHEZ, L. CAMPA, MARIA FUENCISLA PILAR CUELLAR, ELSA MARIA VALDIZAN RUIZ, MARIA ELENA CASTRO FERNANDEZ, A. ADELL, ANGEL PAZOS CARRO, ALVARO MARCELINO DIAZ MARTINEZ

01/10/2014

Behavioural characterization of 5-ht4 receptor knockout mice: implications for anxiety and depression

Conference object

Basic & Clinical Pharmacology & Toxicology, 2014, 115(S2), 39

Authorship: ALVARO MARCELINO DIAZ MARTINEZ, JOSEP AMIGO RIU, ELSA MARIA VALDIZAN RUIZ, ANA MARTIN VEGA, MARIA FUENCISLA PILAR CUELLAR, ANGEL PAZOS CARRO, V. COMPAN, MARIA ELENA CASTRO FERNANDEZ

2014

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Detalle Investigador

MARIA ELENA CASTRO FERNANDEZ

Identifiers

Brain matrix metalloproteinase-9 activity is altered in the corticosterone mouse model of depression

Inhibition of prolyl oligopeptidase restores prohibitin 2 levels in psychosis models: relationship to cognitive deficits in schizophrenia

5-ht4 receptors are not involved in the effects of fluoxetine in the corticosterone model of depression

mTOR knockdown in the infralimbic cortex evokes a depressive-like state in mouse

Cannabidiol antidepressant-like effect in the lipopolysaccharide model in mice: Modulation of inflammatory pathways

Increased vulnerability to impulsive behavior after streptococcal antigen exposure and antibiotic treatment in rats

ß-Catenin Role in the Vulnerability/Resilience to Stress-Related Disorders Is Associated to Changes in the Serotonergic System

Targeting B-Catenin in GLAST-Expressing Cells: Impact on Anxiety and Depression-Related Behavior and Hippocampal Proliferation

S 47445 counteracts the behavioral manifestations and hippocampal neuroplasticity changes in bulbectomized mice

Role of serotonin and noradrenaline in the rapid antidepressant action of ketamine

Effect of cannabis on weight and metabolism in first-episode non-affective psychosis: results from a three-year longitudinal study

Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics

The endocannabinoid system in mental disorders: Evidence from human brain studies

Enhanced stress response in 5-HT1AR overexpressing mice: altered HPA function and hippocampal long-term potentiation

Chronic citalopram administration desensitizes prefrontal cortex but not somatodendritic ?2-adrenoceptors in rat brain

Antidepressant-like effects of the AMPA potentiator S47445 are associated with changes in hippocampal BDNF and mTOR signaling in bulbectomy mouse model

The glial phosphorylase of glycogen isoform is reduced in the dorsolateral prefrontal cortex in chronic schizophrenia

The absence of 5-HT4 receptors modulates depression- and anxiety-like responses and influences the response of fluoxetine in olfactory bulbectomised mice: Adaptive changes in hippocampal neuroplasticity markers and 5-HT1A autoreceptor

Autoradiographic Visualization of G Protein-Coupled Receptors in Brain

Signaling pathways involved in antidepressant-induced cell proliferation and synaptic plasticity

Serotonin 5-HT4 receptors: A new strategy for developing fast acting antidepressants?

Serotonin 5-HT4 receptors: A new strategy for developing fast acting antidepressants?

Effects of chronic cannabidiol on serotonin/glutamate cortical release and molecular signaling pathways in bulbectomised depressed mice

Behavioural characterization of 5-ht4 receptor knockout mice: implications for anxiety and depression

CARACTERIZACION DE UN MODELO ANIMAL DE DEPRESION INTEGRANDO OBESIDAD E INFLAMACION: EFECTO DEL CANNABIDIOL Pry PID2021-127497OB-I00 financiado por MICIU/AEI /10.13039/501100011033 y por FEDER, UE

METALOPROTEINASA-9 Y DEPRESION:ESTUDIO EN MODELO ANIMAL Y MUESTRAS CEREBRALES HUMANAS POSTMORTEM,Y PAPEL EN EL MECANISMO DE ACCION DE ANTIDEPRESIVOS DE ACCION RAPIDA.RTI2018-097534-B-I00/MCIN/AEI/10.13039/501100011033/ FEDER"Una manera de hacer Europa"

ESTUDIO DE LA POTENCIALIDAD DE MERCADO DE EXTRACTOS DE HELECHO COMÚN

CANNABIDIOL COMO ACELERADOR DE LA RESPUESTA FARMACOLOGICA ANTIDEPRESIVA: UNA VIA HACIA LA IDENTIFICACIÓN DE LOS MECANISMOS CELULARES IMPLICADOS EN LA DEPRESIÓN (SAF2015-67457-R) (MINECO/FEDER, UE)

PUESTA A PUNTO DE ENSAYOS CELULARES Y MODELOS ANIMALES PARA IDENTIFICAR DIANAS MOLECULARES DE INTERÉS EN TRASTORNOS PSIQUIÁTRICOS

MECANISMOS DE NEUROPLASTICIDAD INVOLUCRADOS EN LA RESPUESTA ANTIDEPRESIVA RÁPIDA DE LOS AGONISTAS DE RECEPTOR 5-HT4: PAPEL DE LAS VÍAS DE WNT-BETA-CATENINA Y MTOR (SAF2011-25020)

PUESTA A PUNTO DE ENSAYOS CELULARES Y CARACTERIZACIÓN DE LOS MODELOS ANIMALES DE TRANSTORNOS PSIQUIATRICOS

Metaloproteinasa-9 y depresión: estudio en un modelo animal y en muestras cerebrales humanas post-mortem, y papel en el mecanismo de acción de antidepresivos de acción rápida

Influencia del Receptor 5-HT4 en la Depresión y en el Mecanismo de Acción de los Fármacos Antidepresivos.

Modulación de los Receptores 5-HT4 y 5-HT1B tras el Tratamiento Crónico con Fármacos Antidepresivos