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Colorimetric fusion of attenuation and birefringence in OCT signatures: a screening tool for evaluating muscular degradation in alpha-sarcoglican deficit murine models

Abstract: In this work, intensity and polarization OCT were applied, simultaneously, to alpha-sarcoglycan deficit mice models, and a new visualization technique was implemented, based on encoding the attenuation and birefringence values in the HSV color space. Our samples consisted of 14 ex-vivo mice quadriceps at different disease stages (one, three, and six-month-old mice) and four healthy ones for reference. The healthy muscles present a different birefringence distribution to the dystrophic ones, while attenuation values for both kinds of samples lay in the same range. Nevertheless, the attenuation provides an increase in contrast and textural features that are not visible by only using birefringence, while the latter, encoded in the H coordinate, helps to easily identify damage inside the samples by color.

Otras comunicaciones del congreso o articulos relacionados con autores/as de la Universidad de Cantabria

 Autoría: Mieites V., Pardo A., Gutiérrez-Gutiérrez J.A., Suárez-Calvet X., López-Higuera J.M., Díaz-Manera J., Conde O.M.,

 Congreso: Optical Coherence Imaging Techniques and Imaging in Scattering Media (5º : 2023 : Múnich)

Editorial: SPIE Society of Photo-Optical Instrumentation Engineers

 Fecha de publicación: 11/08/2023

Tipo de publicación: Comunicación a Congreso

 DOI: 10.1117/12.2670555

ISSN: 0277-786X,1996-756X

Url de la publicación: https://doi.org/10.1117/12.2670555

Autores/as

VERONICA MIEITES ALONSO

ARTURO PARDO FRANCO

SUÁREZ CALVET, XAVIER

DÍAZ MANERA, JORDI