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 Detalle_Publicacion

Hyperhomocysteinemia in adult patients: a treatable metabolic condition

Abstract: Hyperhomocysteinemia (HHcy) is recognized as an independent risk factor for various significant medical conditions, yet controversy persists around its assessment and management. The diagnosis of disorders afffecting homocysteine (Hcy) metabolism faces delays due to insufficient awareness of its clinical presentation and unique biochemical characteristics. In cases of arterial or venous thrombotic vascular events, particularly with other comorbidities, it is crucial to consider moderate to severe HHcy. A nutritional approach to HHcy management involves implementing dietary strategies and targeted supplementation, emphasizing key nutrients like vitamin B6, B12, and folate that are crucial for Hcy conversion. Adequate intake of these vitamins, along with betaine supplementation, supports Hcy remethylation. Lifestyle modifications, such as smoking cessation and regular physical activity, complement the nutritional approach to enhance Hcy metabolism. For individuals with HHcy, maintaining a plasma Hcy concentration below 50 ?mol/L consistently is vital to lowering the risk of vascular events. Collaboration with healthcare professionals and dietitians is essential for developing personalized dietary plans addressing the specific needs and underlying health conditions. This integrated approach aims to optimize metabolic processes and reduce the associated health risks.

Otras publicaciones de la misma revista o congreso con autores/as de la Universidad de Cantabria

 Fuente: Nutrients, 2024, 16, 135

Editorial: MDPI

 Año de publicación: 2024

Nº de páginas: 14

Tipo de publicación: Artículo de Revista

ISSN: 2072-6643

Url de la publicación: 10.3390/nu16010135

Autoría

ARRIETA-BANCO, FRANCISCO JESÚS

DIOS FUENTES, ELENA

FORGA-VISA, MARÍA TERESA

MORALES-CONEJO, MONSTSERRAT

PEÑA-QUINTANA, LUIS

VITORIA-MIÑANA, ISIDRO