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Analysis of radiation parameters to control the effects of Nd: YAG laser surgery on gastric malignancies

Abstract: Endoscopic laser surgery provides an advantageous alternative to Argon Plasma Coagulation, endoscopic tweezers or electro-ablation in gastroenterology that facilitates a selective ablation of stomach tumors with an additional hemostatic effect in the surrounding tissue. This coagulation effect can also be employed for the treatment of gastric ulcers. It is mandatory to control the laser parameters regardless of the desired effect, either cancerous tissue ablation or coagulation to prevent ulcerous bleeding, in order to avoid stomach wall perforation or an insufficient therapeutic outcome. Dosimetric models constitute an attractive tool to determine the proper light dose in order to offer a customized therapy planning that optimizes the treatment results. In this work, a model for Nd:YAG laser surgery is applied to predict both the coagulation zone in gastric ulcers and the removal in adenocarcinomas under different laser setups. Results show clear differences in the effective zone of the gastric malignancy affected by both coagulation and ablation. Therefore the current model could be employed in the clinical practice to plan the optimal laser beam parameters to treat a certain type of pathologic stomach tissue with variable morphology and without risk of perforation or undertreated parts.

Other conference communications or articles related to authors from the University of Cantabria

 Authorship: Pelayo-Fernández M., Fanjul-Vélez F., Salas-García I., Hernández-González A., Arce-Diego J.,

 Congress: European Conference on Biomedical Optics: ECBO (2015 : Múnich)

 Publisher: The Optical Society (OSA) - SPIE Society of Photo-Optical Instrumentation Engineers

 Year of publication: 2015

 No. of pages: 5

 Publication type: Conference object

 DOI: 10.1117/12.2183456

 ISSN: 0277-786X,1996-756X

 Spanish project: MAT2012-38664-C02-01

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