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Analysis of thermal effects in endoscopic nanocarriers-based photodynamic therapy applied to esophageal diseases

Abstract: In this work we propose a predictive model that allows the study of thermal effects produced when the optical radiation interacts with an esophageal or stomach disease with gold nanoparticles embedded. The model takes into account light distribution in the tumor tissue by means of a Monte Carlo method. Mie theory is used to obtain the gold nanoparticles optical properties and the thermal model employed is based on the bio-heat equation. The complete model was applied to two types of tumoral tissue (squamous cell carcinoma located in the esophagus and adenocarcinoma in the stomach) in order to study the thermal effects induced by the inclusion of gold nanoparticles.

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Authorship: Salas-García I., Fanjul-Vélez F., Ortega-Quijano N., Wilfert O., Hudcova L., Poliak J., Barcik P., Arce-Diego J.,

Congress: Optical Interactions with Tissue and Cells (25ª); and Terahertz for Biomedical Applications (2014 : San Francisco)

Publisher: SPIE Society of Photo-Optical Instrumentation Engineers

Year of publication: 2014

No. of pages: 6

Publication type: Conference object

DOI: 10.1117/12.2039209

ISSN: 0277-786X,1996-756X

Spanish project: MAT2012-38664-C02-01

Publication Url: https://doi.org/10.1117/12.2039209

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Authorship

IRENE SALAS GARCIA

FELIX FANJUL VELEZ

NOE ORTEGA QUIJANO

WILFERT, O.

HUDCOVA, L.

POLIAK, J.

BARCIK, J.

JOSE LUIS ARCE DIEGO

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