Buscar

Estamos realizando la búsqueda. Por favor, espere...

 Detalle_Publicacion

Optical coherence tomography assessment of vessel wall degradation in aneurysmatic thoracic aortas

Abstract: Optical coherence tomographic images of ascending thoracic human aortas from aneurysms exhibit disorders on the smooth muscle cell structure of the media layer of the aortic vessel as well as elastin degradation. Ex-vivo measurements of human samples provide results that correlate with pathologist diagnosis in aneurysmatic and control aortas. The observed disorders are studied as possible hallmarks for aneurysm diagnosis. To this end, the backscattering profile along the vessel thickness has been evaluated by fitting its decay against two different models, a third order polynomial fitting and an exponential fitting. The discontinuities present on the vessel wall on aneurysmatic aortas are slightly better identified with the exponential approach. Aneurysmatic aortic walls present uneven reflectivity decay when compared with healthy vessels. The fitting error has revealed as the most favorable indicator for aneurysm diagnosis as it provides a measure of how uniform is the decay along the vessel thickness.

Otras comunicaciones del congreso o articulos relacionados con autores/as de la Universidad de Cantabria

 Autoría: Real E., Eguizabal A., Pontón A., Val-Bernal J., Mayorga M., Revuelta J., López-Higuera J., Conde O.,

 Congreso: European Conference on Biomedical Optics, ECBO (2013 : Múnich, Alemania)

Editorial: SPIE Society of Photo-Optical Instrumentation Engineers-The Optical Society (OSA)

 Fecha de publicación: 01/05/2013

Nº de páginas: 7

Tipo de publicación: Comunicación a Congreso

 DOI: 10.1117/12.2032592

ISSN: 0277-786X,1996-756X

Proyecto español: FIS2010-19860 ; TEC2010-20224-C02-02

Url de la publicación: https://doi.org/10.1117/12.2032592

Autores/as

EUSEBIO REAL PEÑA

ALMA EGUIZABAL AGUADO

ALEJANDRO PONTON CORTINA

JOSE FERNANDO VAL BERNAL

MARTA M. MAYORGA FERNANDEZ