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Standardization procedure for flow cytometry data harmonization in prospective multicenter studies

Abstract: One of the most challenging objective for clinical cytometry in prospective multicenter immunomonitoring trials is to compare frequencies, absolute numbers of leukocyte populations and further the mean fluorescence intensities of cell markers, especially when the data are generated from different instruments. Here, we describe an innovative standardization workflow to compare all data to carry out any large-scale, prospective multicentric flow cytometry analysis whatever the duration, the number or type of instruments required for the realization of such projects

Other publications of the same journal or congress with authors from the University of Cantabria

 Fuente: Scientific Reports 10, 11567 (2020).

Publisher: Nature Publishing Group

 Year of publication: 2020

No. of pages: 8

Publication type: Article

 DOI: 10.1038/s41598-020-68468-3

ISSN: 2045-2322

Publication Url: https://doi.org/10.1038/s41598-020-68468-3

Authorship

LUCAS LE LANN

PIERRE-EMMANUEL JOUVE

MARTA ALARCÓN-RIQUELME

CHRISTOPHE JAMIN

JACQUES-OLIVIER PERS