Characterization of the Antitumor Potential of Extracts of Cannabis sativa Strains with High CBD Content in Human Neuroblastoma

Sánchez-Sánchez L, García J, Fernández R, Noskova E, Egiguren-Ortiz J, Gulak M, Ochoa E, Laso A, Oiarbide M, Santos JI, Fe Andrés M, González-Coloma A, Adell A, Astigarraga E, Barreda-Gómez G.

​Int J Mol Sci. 2023 Feb 14;24(4):3837.​
​

Ver más

Acute Stress-Induced Changes in the Lipid Composition of Cow's Milk in Healthy and Pathological Animals

Garro-Aguilar Y, Fernández R, Calero S, Noskova E, Gulak M, de la Fuente M, Adell A, Simón E, Muzquiz U, Rodríguez-Piñón D, Astigarraga E, Barreda-Gómez G.

​Molecules. 2023 Jan 18;28(3):980.​​​

Ver más

Screening System of Cannabis sativa Extracts Based on Their Mitochondrial Safety Profile Using Cytochrome c Oxidase Activity as a Biomarker

Noskova E, Fernández R, García J, Ochoa E, Domínguez-Fernández C, Adell A, Laso A, Andrés MF, González-Coloma A, Astigarraga E, Barreda-Gómez G.

Int J Mol Sci​​. 2023 Jan 10;24(2):1315.​
​​​

Ver más

Molecular Signaling Mechanisms for the Antidepressant Effects of NLX-101, a Selective Cortical 5-HT 1A Receptor Biased Agonist

Cabanu S, Pilar-Cuéllar F, Zubakina P, Florensa-Zanuy E, Senserrich J, Newman-Tancredi A, Adell A.

Pharmaceuticals (Basel). 2022 Mar 10;15(3):337.

Ver más

Effects of Acute Stress on the Oscillatory Activity of the Hippocampus-Amygdala-Prefrontal Cortex Network

Merino E, Raya-Salom D, Teruel-Martí V, Adell A, Cervera-Ferri A, Martínez-Ricós J.

Neuroscience. 2021 Sep 17:S0306-4522(21)00476-0. doi: 10.1016/j.neuroscience.2021.09.009. Online ahead of print.

Ver más

mTOR Knockdown in the Infralimbic Cortex Evokes A Depressive-like State in Mouse

Garro-Martínez E, Fullana MN, Florensa-Zanuy E, Senserrich J, Paz V, Ruiz-Bronchal E, Adell A, Castro E, Díaz Á, Pazos Á, Bortolozzi A, Pilar-Cuéllar F.

​Int J Mol Sci. 2021 Aug 12;22(16):8671. doi: 10.3390/ijms22168671.

Ver más

Structural connectivity and subcellular changes after antidepressant doses of ketamine and Ro 25-6981 in the rat: an MRI and immuno-labeling study

Pascual-Antón R, Blasco-Serra A, Muñoz-Moreno E, Pilar-Cuéllar F, Garro-Martínez E, Florensa-Zanuy E, López-Gil X, Campa VM, Soria G, Adell A.

​Brain Struct Funct. 2021 Aug 7. doi: 10.1007/s00429-021-02354-0.

Ver más

Structural connectivity and subcellular changes after antidepressant doses of ketamine and Ro 25-6981 in the rat

Pascual-Antón R, Blasco-Serra A, Muñoz-Moreno E, Pilar-Cuéllar F, Garro-Martínez E, Florensa-Zanuy E, López-Gil X, Campa VM, Soria G, Adell A.

Brain Struct Funct. 2021 Nov;226(8):2603-2616. 

Ver más

Cannabidiol antidepressant-like effect in the lipopolysaccharide model in mice: Modulation of inflammatory pathways

Florensa-Zanuy E, Garro-Martínez E, Adell A, Castro E, Díaz Á, Pazos Á, Mac-Dowell KS, Martín-Hernández D, Pilar-Cuéllar F.

​Biochem Pharmacol. 2021 Mar;185:114433. doi: 10.1016/j.bcp.2021.114433. Epub 2021 Jan 26.

Ver más

Role of Serotonin and Noradrenaline in the Rapid Antidepressant Action of Ketamine.

López-Gil X, Jiménez-Sánchez L, Campa L, Castro E, Frago C, Adell A.

​ACS Chem Neurosci. 2019 Jul 17;10(7):3318-3326. doi: 10.1021/acschemneuro.9b00288. Epub 2019 Jun 18.​

Ver más

β-Catenin Role in the Vulnerability/Resilience to Stress-Related Disorders Is Associated to Changes in the Serotonergic System.

Garro-Martínez E, Vidal R, Adell A, Díaz Á, Castro E, Amigó J, Gutiérrez-Lanza R, Florensa-Zanuy E, Gómez-Acero L, Taketo MM, Pazos Á, Pilar-Cuéllar F.

Mol Neurobiol. 2019 Dec 10. doi: 10.1007/s12035-019-01841-0. [Epub ahead of print]

Ver más

Signaling pathways responsible for the rapid antidepressant-like effects of a GluN2A-preferring NMDA receptor antagonist.

Gordillo-Salas M, Pilar-Cuéllar F, Auberson YP, Adell A.

​Transl Psychiatry. 2018 Apr 18;8(1):84. doi: 10.1038/s41398-018-0131-9.​

Ver más

Behavioral, neurochemical and molecular changes after acute deep brain stimulation of the infralimbic prefrontal cortex.

Jiménez-Sánchez L, Linge R, Campa L, Valdizán EM, Pazos Á, Díaz Á, Adell A.

Neuropharmacology. 2016 Sep;108:91-102.​

Ver más

Characterization of oscillatory changes in hippocampus and amygdala after deep brain stimulation of the infralimbic prefrontal cortex.

Cervera-Ferri A, Teruel-Martí V, Barceló-Molina M, Martínez-Ricós J, Luque-García A, Martínez-Bellver S, Adell A.

​[PubMed] Physiol Rep. 2016 Jul;4(14). pii: e12854. doi: 10.14814/phy2.12854.

Ver más

Activation of AMPA Receptors Mediates the Antidepressant Action of Deep Brain Stimulation of the Infralimbic Prefrontal Cortex.

Jiménez-Sánchez L, Castañé A, Pérez-Caballero L, Grifoll-Escoda M, López-Gil X, Campa L, Galofré M, Berrocoso E, Adell A.

Cereb Cortex. 2016 Jun;26(6):2778-89.​ ​[PubMed]

Ver más

Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors.

Linge R, Jiménez-Sánchez L, Campa L, Pilar-Cuéllar F, Vidal R, Pazos A, Adell A, Díaz Á. Neuropharmacology. 2016 Apr;103:16-26. doi: 10.1016/j.neuropharm.2015.12.017.

​[PubMed]

Ver más

Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors.

Linge R, Jiménez-Sánchez L, Campa L, Pilar-Cuéllar F, Vidal R, Pazos A, Adell A, Díaz Á.

​Neuropharmacology. 2016 Apr;103:16-26. doi: 10.1016/j.neuropharm.2015.12.017. Epub 2015 Dec 19.

Ver más

Revisiting the role of raphe and serotonin in neuropsychiatric disorders.

Adell A. (2015) J Gen Physiol 145: 257-259.

​[PubMed]

Ver más

The role of GluN2A and GluN2B subunits on the effects of NMDA receptor antagonists in modeling schizophrenia and treating refractory depression.

Jiménez-Sánchez L., Campa L., Auberson Y.P. and Adell A. (2014) Neuropsychopharmacology 39, 2673–2680.

​[PubMed]

Ver más

Expression of 5-HT2A receptors in prefrontal cortex pyramidal neurons projecting to nucleus accumbens. Potential relevance for atypical antipsychotic action.

Mocci G., Jiménez-Sánchez L., Adell A. and Artigas F. (2014) Neuropharmacology 79: 49-58.

​[PubMed]

Ver más

Blockade of MK-801-induced heat shock protein 72 in rat brain by antipsychotic and monoaminergic agents targeting D2, 5-HT1A, 5-HT2A and α1-adrenergic receptors.

Romón T., Planas A.M. and Adell A. (2014) CNS Neurol. Disord. – Drug Targets 13: 104-111.

​[PubMed]

Ver más

Role of prefrontal cortex in the pathophysiology and treatment of depression and schizophrenia. In: Neurobiology of Mood Disorders.

López-Gil X., Jiménez-Sánchez L. and Adell A. (2013) Guiard B.P. and Dremencov E. (Eds.). Bentham Science Publishers, Sharjah, pp. 139-173.

Ver más

Importance of interhemispheric prefrontal connection in the effects of noncompetitive NMDA receptor antagonists.

López-Gil X., Jiménez-Sánchez L., Romón T., Campa L., Artigas F. and Adell A. (2012) Int. J. Neuropsychopharmacol. 15: 945-956.

​[PubMed]

Ver más

Is the acute NMDA receptor hypofunction a valid model of schizophrenia?

Adell A., Jiménez-Sánchez L., López-Gil X. and Romón T. (2012) Schizophrenia Bull. 38: 9-14.

​ [PubMed]

Ver más

Expression of parvalbumin and glutamic acid decarboxylase-67 after acute administration of MK-801. Implications for the NMDA hypofunction model of schizophrenia.

Romón T., Mengod G. and Adell A. (2011) Psychopharmacology 217: 231-238.

​[PubMed]

Ver más

Microdialysis.

Adell A. and Artigas F. (2010) In: Encyclopedia of Psychopharmacology. Stolerman I.P. (Ed.). Springer-Verlag, Berlin, pp. 769-775.

Ver más

Lu-AA21004, a multimodal serotonergic agent, for the potential treatment of depression and anxiety.

Adell A. (2010) Idrugs 13: 900-910.

​[PubMed]

Ver más

In vitro and in vivo activation of astrocytes by amyloid β is potentiated by pro-oxidant agents.

García-Matas S., de Vera N., Ortega-Aznar A., Marimon J.M., Adell A., Planas A.M., Cristòfol R. and Sanfeliu C. (2010) J. Alzheimer's Dis. 20: 229-245.

​[PubMed]

Ver más

Serotonin interaction with other transmitter systems. In: Handbook of Behavioral Neurobiology of Serotonin.

Adell A., Bortolozzi A., Díaz-Mataix L., Santana N. and Artigas F. (2010) Müller C.P. and Jacobs B.L. (Eds.). Elsevier, Amsterdam, pp. 259-276.

Ver más

Unraveling monoamine receptors involved in the action of typical and atypical antipsychotics on glutamatergic and serotonergic transmission in prefrontal cortex.

López-Gil X., Artigas F. and Adell A. (2010) Curr. Pharm. Des. 16: 502-515.

​[PubMed]

Ver más

New strategies in the search of antipsychotic drugs.

Adell A. (2010) Curr. Pharm. Des. 16: 486-487.

​[PubMed]

Ver más