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DispForm.aspx66869/30/2020 9:13:09 AMhttps://web.unican.es/ibbtec/en-us/Lists/Members/AllItems.aspxFalsestring;#Jaime González Gutiérrez de la Concha141IBBTEC17_MemberJaime González Gutiérrez de la Conchajaime.gonzalez@unican.es942 206 799 Ext.132
Arechaga Iturregui, Iñaki84828/25/2020 7:54:34 AMhttps://web.unican.es/ibbtec/en-us/Lists/Members/AllItems.aspxFalsestring;#Iñaki Arechaga Iturregui (IP)2https://web.unican.es/ibbtec/es-es/PublishingImages/members/TN-Arechaga.jpg, https://web.unican.es/ibbtec/es-es/PublishingImages/members/TN-Arechaga.jpg<h2 style="text-align&#58;center;"><span class="ms-rteThemeForeColor-2-0"><strong>​Molecular Motors in Nanobiotechnology</strong></span></h2><p><img src="/ibbtec/es-es/PublishingImages/GrupoElena.jpg" alt="" style="margin&#58;5px;width&#58;720px;" /><br></p><h3><span class="ms-rteThemeForeColor-5-5">Research interests</span><br></h3><ul style="margin&#58;1em;padding&#58;0px;border&#58;0px;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;list-style-position&#58;initial;list-style-image&#58;initial;color&#58;#474f51;"><li style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Structural and biochemical approach into the molecular mechanism of RecA/AAA+ motors (<span style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;">A</span>TPases&#160;<span style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;">A</span>ssociated to a large variety of cellular&#160;<span style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;">A</span>ctivities (i.e. DNA unwinding, protein folding, DNA transport…)&#160;</span></li><li style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><p style="padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Inhibitors of bacterial conjugation to prevent the dissemination of antibiotic resistance genes</span></p></li><li style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2" style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;">Protein nanopores for DNA sequencing and susbstrate secretion</span></li><li style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Electron microscopy of large membrane protein complexes&#160;</span></li></ul><p style="padding&#58;0px;border&#58;0px;font-stretch&#58;inherit;vertical-align&#58;baseline;color&#58;#474f51;"></p><p style="padding&#58;0px;border&#58;0px;font-stretch&#58;inherit;vertical-align&#58;baseline;color&#58;#474f51;"></p><h3><span class="ms-rteThemeForeColor-5-5">Funding</span><br></h3><p style="padding&#58;0px;border&#58;0px;font-stretch&#58;inherit;vertical-align&#58;baseline;color&#58;#474f51;"></p><ul style="margin&#58;1em;padding&#58;0px;border&#58;0px;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;list-style-position&#58;initial;list-style-image&#58;initial;color&#58;#474f51;"><li style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><p style="padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;"><span lang="ES-TRAD" class="ms-rteThemeFontFace-1 ms-rteFontSize-2" style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;">Título del proyecto&#58; “Aplicaciones biomédicas y biotecnológicas de motores moleculares implicados en la transferencia de ADN y proteínas a través de membranas biológicas”<br>Entidad financiadora&#58;&#160;&#160; Ministerio de Economía, Industria y Competitividad<br>Referencia&#58; BFU2016-78521-R<br>Duración&#58;desde 30/12/2016 hasta 29/12/2019<br>Investigadores responsables&#58; Dr. Elena Cabezón e Ignacio Arechaga</span></p></li><li style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><p style="padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;text-align&#58;justify;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Título del proyecto&#58; &quot;Aplicación de un motor que transloca ssDNA en plataformas de secuenciación de tercera generación&quot;<br>Entidad financiadora&#58; Ministerio de Economía y Competitividad<br>Referencia&#58; BFU2014-61823-EXP<br>Duración&#58; desde 01/09/2015 hasta 31/08/2017<br>Investigador responsable&#58; Dr. Elena Cabezón</span></p></li></ul><ul dir="ltr" style="margin&#58;1em;padding&#58;0px;border&#58;0px;font-family&#58;&quot;yanone kaffeesatz&quot;;font-size&#58;18px;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;list-style-position&#58;initial;list-style-image&#58;initial;color&#58;#474f51;text-align&#58;left;"><li style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><p style="padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2"><span style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"></span>Título del proyecto&#58; &quot;Morfogénesis de membranas bacterianas y mitocondriales&#58; en busca del eslabón perdido&quot;</span></p><p style="padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Entidad financiadora&#58; Ministerio de Economía y Competitividad&#160;</span></p><p style="padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Referencia &#58; BFU2013_49486-EXP</span></p><p style="padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Duración&#58; 2014-2016</span></p><p style="padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Investigador responsable&#58; Dr. Ignacio Arechaga</span></p></li><li style="margin&#58;0px;padding&#58;0px;border&#58;0px;font-family&#58;inherit;font-size&#58;inherit;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><p style="padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Título del proyecto&#58; &quot;Mecanismos moleculares y evolutivos en motores moleculares que translocan ADN y proteínas&quot;</span></p><p style="padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Entidad financiadora&#58; Ministerio de Economía y Competitividad</span></p><p style="padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Referencia&#58; BFU2011-22874</span></p><p style="padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Duración&#58;desde 01/01/2012 hasta 31/12/2015&#160;</span></p><p style="padding&#58;0px;border&#58;0px;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Investigador responsable&#58; Dr. Elena Cabezón</span></p></li></ul>IBBTEC17_MemberIñakiArechaga Iturregui (IP)ignacio.arechaga@unican.es942 202033
León Serrano, Javier85019/30/2020 8:50:42 AMhttps://web.unican.es/ibbtec/en-us/Lists/Members/AllItems.aspxFalsestring;#Javier León Serrano (IP)8https://web.unican.es/ibbtec/es-es/PublishingImages/members/Leon-TN.jpg, https://web.unican.es/ibbtec/es-es/PublishingImages/members/Leon-TN.jpg<p>​<span style="color&#58;#373f42;font-size&#58;23.4px;">Tra</span><span style="color&#58;#373f42;font-size&#58;23.4px;">nscriptional control of cancer and regulation of cell division&#160;group</span></p><p><span style="color&#58;#373f42;font-size&#58;23.4px;"></span><img src="/ibbtec/es-es/PublishingImages/Grupo-Leon-y-Delgado.jpg" alt="" style="margin&#58;5px;width&#58;879px;" /></p><div><p></p><h2>Research lines and interests<br></h2><ul style="margin&#58;1em;padding&#58;0px;border&#58;0px none;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;list-style-position&#58;initial;list-style-image&#58;initial;color&#58;#474f51;"><li style="margin&#58;0px;padding&#58;0px;border&#58;0px none;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Roles of Myc and Myc network proteins Mxd1 and Mnt on cell proliferation and differentiation of hematopoietic and embryonic stem cells&#160;</span></li><li style="margin&#58;0px;padding&#58;0px;border&#58;0px none;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Functional interactions of Myc with cell cycle regulatory proteins</span></li><li style="margin&#58;0px;padding&#58;0px;border&#58;0px none;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Myc target genes in leukemia/lymphoma&#160;</span></li><li style="margin&#58;0px;padding&#58;0px;border&#58;0px none;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2"><span style="margin&#58;0px;padding&#58;0px;border&#58;0px none;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;">&#160;</span>Function of CTCF in the hematopoietic differentiation. We aim to explore the function of CTCF in hematopoietic differentiation through the analysis of their target genes, using cell lines and primary cells. The methodology includes DNA interaction analysis , epigenetic regulation assays, modulation expression, profiling analysis, etc.&#160;</span></li><li style="margin&#58;0px;padding&#58;0px;border&#58;0px none;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">To know the CTCF involvement in hematological malignancies, especially in lymphomas. We use lymphoma cell lines and samples from patients. The aim is to determine if CTCF could be marker for diagnosis or prognosis in hematological neoplasias</span></li></ul><h3 style="margin&#58;0px;color&#58;#96a9b5;padding&#58;0px;border&#58;0px none;font-stretch&#58;inherit;vertical-align&#58;baseline;"><br class="ms-rteThemeFontFace-1 ms-rteFontSize-2"></h3><h2>Funding&#160;</h2><ul style="margin&#58;1em;padding&#58;0px;border&#58;0px none;font-family&#58;&quot;yanone kaffeesatz&quot;;font-size&#58;18px;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;list-style-position&#58;initial;list-style-image&#58;initial;color&#58;#474f51;"><li style="margin&#58;0px;padding&#58;0px;border&#58;0px none;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Oncoproteínas MYC Y CTCF en el control transcripcional de la diferenciación hematopoyética y en linfoma. SAF2014-53526R. CoIPs&#58; Javier León y M. Dolores Delgado</span></li><li style="margin&#58;0px;padding&#58;0px;border&#58;0px none;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Función de los reguladores transcripcionales CTCF y CTCF-L (BORIS) en la diferenciación hematopoyética normal y patológica. Instituto de Salud Carlos III. FIS11/00397</span></li><li class="MsoNormal" style="margin&#58;0cm 0cm 0pt;padding&#58;0px;border&#58;0px none;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;normal;vertical-align&#58;baseline;text-align&#58;justify;"><p style="padding&#58;0px;border&#58;0px none;font-style&#58;inherit;font-stretch&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">Terapia epigenética en linfomas de células B. Papel de los reguladores de cromatina de la familia CTCF. Entidad financiadora&#58; Celgene S.L.U.</span></p></li><li style="margin&#58;0px;padding&#58;0px;border&#58;0px none;font-family&#58;inherit;font-size&#58;inherit;font-style&#58;inherit;font-stretch&#58;inherit;line-height&#58;inherit;vertical-align&#58;baseline;"><span class="ms-rteThemeFontFace-1 ms-rteFontSize-2">&quot;Red Temática Investigación Cooperativa de Investigación en Cáncer&quot; ISCIII-RETIC RD12/0036/0033. IP&#58; Piero Crespo</span><br></li></ul></div>IBBTEC17_MemberJavierLeón Serrano (IP)javier.leon@unican.es942 201952
Cabezas Isidro, Matilde851310/14/2020 6:59:07 AMhttps://web.unican.es/ibbtec/en-us/Lists/Members/AllItems.aspxFalsestring;#Matilde Cabezas Isidro28IBBTEC17_MemberMatildeCabezas Isidromatilde.cabezas@unican.es942 203930
Campa Fernández, Víctor Manuel85149/30/2020 8:51:46 AMhttps://web.unican.es/ibbtec/en-us/Lists/Members/AllItems.aspxFalsestring;#Víctor Manuel Campa Fernández29https://web.unican.es/ibbtec/es-es/PublishingImages/members/Campa-TN.jpg, https://web.unican.es/ibbtec/es-es/PublishingImages/members/Campa-TN.jpgIBBTEC17_MemberVíctor ManuelCampa Fernándezvictormanuel.campa@unican.es942 206799 ext. 109
Castillo Díaz, María Josefa852410/14/2020 6:58:05 AMhttps://web.unican.es/ibbtec/en-us/Lists/Members/AllItems.aspxFalsestring;#María Josefa Castillo Díaz34IBBTEC17_MemberMaría JosefaCastillo Díazjosefa.castillo@unican.es942 206854
Fernández López, Raúl85329/30/2020 8:52:58 AMhttps://web.unican.es/ibbtec/en-us/Lists/Members/AllItems.aspxFalsestring;#Raúl Fernández López42https://web.unican.es/ibbtec/es-es/PublishingImages/members/FdezLopez-TN.jpg, https://web.unican.es/ibbtec/es-es/PublishingImages/members/FdezLopez-TN.jpgIBBTEC17_MemberRaúlFernández Lópezraul.fernandez@unican.es942 206799 ext. 120
Gómez Herrero, Iván 85489/30/2020 8:54:45 AMhttps://web.unican.es/ibbtec/en-us/Lists/Members/AllItems.aspxFalsestring;#Iván Gómez Herrero58https://web.unican.es/ibbtec/es-es/PublishingImages/members/Herrero-TN.jpg, https://web.unican.es/ibbtec/es-es/PublishingImages/members/Herrero-TN.jpgIBBTEC17_MemberIván Gómez Herreroivan.gomez@unican.es942 206799 ext. 124
Lozano Gordillo, Luis Miguel85649/30/2020 8:55:45 AMhttps://web.unican.es/ibbtec/en-us/Lists/Members/AllItems.aspxFalsestring;#Luis Miguel Lozano Gordillo70IBBTEC17_MemberLuis MiguelLozano Gordilloluismiguel.lozano@unican.es942 206859
Luque Jiménez, María Del Rocío85659/30/2020 8:55:56 AMhttps://web.unican.es/ibbtec/en-us/Lists/Members/AllItems.aspxFalsestring;#María Del Rocío Luque Jiménez71https://web.unican.es/ibbtec/es-es/PublishingImages/members/luque-TN2.jpg, https://web.unican.es/ibbtec/es-es/PublishingImages/members/luque-TN2.jpgIBBTEC17_MemberMaría Del RocíoLuque Jiménezrocio.luque@unican.es942 206799 ext. 117