Mass sequencing or NGS (Next Generation Sequencing) is a modern technology that allows to identify a large amount of DNA sequence at a very low cost, using a lesser amount of genetic material and faster response than previous methods.
Its high resolution capacity has allowed a high impact in applied areas, such as diagnostic and preventive medicine, becoming a common-use technology. In addition, it constitutes an important tool in environmental sciences and the agri-food sector, among others.
The Massive Sequencing Service (MSS) at IBBTEC makes available this modern technology to the scientific community and the industrial sector, allowing to execute biological research projects or to solve specific problems of the industry, like control of fermentation processes, biological treatments of water or waste, identification of animal and plant species, etc. In addition, the highly qualified MSS team brings its extensive experience and offers specialized technical advice to bring all the possibilities offered by this technology in any application of interest.
Optical microscopes are one of the most valuable tools to carry out life science research projects. In addition, the motorization of the equipment and the adoption of the digital format in the capture and processing of the images have assumed a qualitative and quantitative leap, greatly expanding its possible applications.
There are many applications of this technology. Examples are quantification and tracking of particles, study of cellular processes such as viability, migration, proliferation, toxicity or apoptosis, molecular studies in vivo, by using biosensors or advanced techniques such as FRAP (Fluorescence Recovery Affer Photobleachin) and FRET (Föster Resonance Energy Transfer), and pharmacological studies of the subcellular localization and the kinetics of drugs and their receptors.
The Advanced Optic Microscopy Service at IBBTEC has advanced equipment and highly qualified personnel, and it allows to tackle projects that require the most modern microscopy techniques, both in fixed and live cell samples. It offers training in the management of equipment, assistance and advice in the realization of advanced techniques, as well as the processing, analysis and quantification of the acquired images.
The use of cellular models is an essential tool for carrying out biomedical and biotechnology research projects. They allow to study the cellular activity, the intracellular flow, the cellular interactions, among others, in diverse areas of research virology, cancer, immunology, protein engineering, interaction and cellular signalling, cellular differentiation and development, as well as diagnostic and medical applications, also of industrial and agri-food interest.
The IBBTEC has two laboratories dedicated to cell cultures, equipped with laminar flow hoods and incubators with temperature, humidity and CO pressure control. In addition, some of these equipment have nitrogen pressure to carry out cell cultures in hypoxia conditions. To guarantee a high quality service, these facilities are subject to access control and strict safety and cleaning measures, in order to reduce the risk of external contamination.
In order for research groups to focus on their R&D projects, it is necessary that routine laboratory tasks be carried out by support services with highly qualified technicians.
The IBBTEC Support Laboratory produces reagents, solutions and culture media. In addition, support for researchers includes the production of DNA preparations, competent bacteria cells for their transformation, genotyping of experimental animals and protein purification. Finally, the support laboratory is destined to the collection, cleaning and sterilization of the lab material of the research groups installed in the IBBTEC, as well as to the preparation of the plastic material of routine use in the laboratories.
Instituto de Biomedicina y Biotecnología de Cantabria.
PCTCAN - Cl. Albert Einstein, 22